BDBM459003 US10759794, Example 37

SMILES Clc1ccc(cc1)-c1nc2ccccn2c1CN1CCN(CC1)C(=O)c1ccccc1Cl

InChI Key InChIKey=WBKYNZJRUXTLGA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 459003   

TargetPotassium channel subfamily K member 9(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM459003(US10759794, Example 37)
Affinity DataIC50: 60nMAssay Description:The investigations on the inhibition of the recombinant TASK-1 and TASK-3 channels were carried out using stably transfected CHO cells. Here, the com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2021
Entry Details
US Patent

TargetPotassium channel subfamily K member 3(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM459003(US10759794, Example 37)
Affinity DataIC50: 370nMAssay Description:The investigations on the inhibition of the recombinant TASK-1 and TASK-3 channels were carried out using stably transfected CHO cells. Here, the com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2021
Entry Details
US Patent