BDBM459189 US10759799, Compound 15

SMILES Cn1ncc-2c1CNCc1cccc(c1)-c1cccc3[nH]c(nc13)-c1n[nH]c3ccc-2cc13

InChI Key InChIKey=WYAQZEMORLXDIK-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 459189   

LigandPNGBDBM459189(US10759799, Compound 15)
Affinity DataEC50:  111nMAssay Description:The DYRK1A kinase assay was run using the Ser/Thr 18 peptide Z-lyte assay kit according to manufacturer's instructions (Life Technologies a Divis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2021
Entry Details
Go to US Patent

TargetGlycogen synthase kinase-3 beta(Human)
Samumed

US Patent
LigandPNGBDBM459189(US10759799, Compound 15)
Affinity DataEC50:  10nMAssay Description:The GSK3β kinase assay is run using the Ser/Thr 09 peptide Z-lyte assay kit according to manufacturer's instructions (Life Technologies a Di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2021
Entry Details
Go to US Patent