BDBM461368 US10774068, Example 74::US11427560, Example 74

SMILES CCOc1cc2ncc(C#N)c(Nc3ccc(OCc4ncccc4C)cc3Br)c2cc1NC(=O)CCCN(C)C

InChI Key InChIKey=VSSCQAQVCRKCMQ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 461368   

TargetSerine/threonine-protein kinase 3(Human)
The Scripps Research Institute

US Patent
LigandPNGBDBM461368(US10774068, Example 74 | US11427560, Example 74)
Affinity DataIC50: 100nMAssay Description:MST1 and MST2 biochemical LanthaScreen Eu Kinase Binding Assay was based on the binding and displacement of kinase tracer to the kinase of interest. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2021
Entry Details
US Patent

TargetSerine/threonine-protein kinase 4(Human)
The Scripps Research Institute

US Patent
LigandPNGBDBM461368(US10774068, Example 74 | US11427560, Example 74)
Affinity DataIC50: 100nMAssay Description:MST1 and MST2 biochemical LanthaScreen Eu Kinase Binding Assay was based on the binding and displacement of kinase tracer to the kinase of interest. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2021
Entry Details
US Patent

TargetSerine/threonine-protein kinase 4(Human)
The Scripps Research Institute

US Patent
LigandPNGBDBM461368(US10774068, Example 74 | US11427560, Example 74)
Affinity DataIC50: 100nMAssay Description:MST1 and MST2 biochemical LanthaScreen Eu Kinase Binding Assay was based on the binding and displacement of kinase tracer to the kinase of interest. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2022
Entry Details
US Patent

TargetSerine/threonine-protein kinase 3(Human)
The Scripps Research Institute

US Patent
LigandPNGBDBM461368(US10774068, Example 74 | US11427560, Example 74)
Affinity DataIC50: 100nMAssay Description:MST1 and MST2 biochemical LanthaScreen Eu Kinase Binding Assay was based on the binding and displacement of kinase tracer to the kinase of interest. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2022
Entry Details
US Patent