BDBM461968 Preparation of N-(17-methylmorphinan-3-yl)methanesulfonamide ::US10766864, Example 37

SMILES CN1CC[C@]23CCCC[C@H]2[C@H]1Cc1ccc(NS(C)(=O)=O)cc31

InChI Key InChIKey=RHKNNDFXUCSIKD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 461968   

TargetMu-type opioid receptor(Human)
Nektar Therapeutics

US Patent
LigandPNGBDBM461968(Preparation of N-(17-methylmorphinan-3-yl)methanes...)
Affinity DataIC50: 550nMAssay Description:Affinities of various compounds were measured in vitro using competitive radioligand binding assays. Serial dilutions of test compounds were incubate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2021
Entry Details
US Patent