BDBM461971 Preparation of tert-butyl (17-methylmorphinan-3-yl)carbamate ::US10766864, Example 40

SMILES CN1CC[C@]23CCCC[C@H]2[C@H]1Cc1ccc(NC(=O)OC(C)(C)C)cc31

InChI Key InChIKey=PXVPDOBANIVJQM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 461971   

TargetMu-type opioid receptor(Human)
Nektar Therapeutics

US Patent
LigandPNGBDBM461971(Preparation of tert-butyl (17-methylmorphinan-3-yl...)
Affinity DataIC50: 550nMAssay Description:Affinities of various compounds were measured in vitro using competitive radioligand binding assays. Serial dilutions of test compounds were incubate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2021
Entry Details
US Patent