BDBM461975 Preparation of 17-methyl-3-(1H-pyrazol-4-yl)morphinan ::US10766864, Example 44

SMILES CN1CC[C@]23CCCC[C@H]2[C@H]1Cc1ccc(cc31)-c1cn[nH]c1

InChI Key InChIKey=BWUGXOANMVYZRB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 461975   

TargetMu-type opioid receptor(Human)
Nektar Therapeutics

US Patent
LigandPNGBDBM461975(Preparation of 17-methyl-3-(1H-pyrazol-4-yl)morphi...)
Affinity DataIC50: 55nMAssay Description:Affinities of various compounds were measured in vitro using competitive radioligand binding assays. Serial dilutions of test compounds were incubate...More data for this Ligand-Target Pair
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Date in BDB:
4/26/2021
Entry Details
US Patent