BDBM461989 Preparation of N-{6-[2-(2-methoxyethoxy)ethoxy]pyridin-3-yl}-17-methylmorphinan-3-amine ::US10766864, Example 58

SMILES COCCOCCOc1ccc(Nc2ccc3C[C@@H]4[C@@H]5CCCC[C@]5(CCN4C)c3c2)cn1

InChI Key InChIKey=DCGOBNGIKSHTOP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 461989   

TargetMu-type opioid receptor(Human)
Nektar Therapeutics

US Patent
LigandPNGBDBM461989(Preparation of N-{6-[2-(2-methoxyethoxy)ethoxy]pyr...)
Affinity DataIC50: 55nMAssay Description:Affinities of various compounds were measured in vitro using competitive radioligand binding assays. Serial dilutions of test compounds were incubate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2021
Entry Details
US Patent