BDBM462005 Preparation of (5α)-5-{2-[2-(2-methoxyethoxy)ethoxy]ethoxy}-17-methylmorphinan-3-ol ::US10766864, Example 75

SMILES COCCOCCOCCO[C@H]1CCC[C@H]2[C@H]3Cc4ccc(O)cc4[C@@]12CCN3C

InChI Key InChIKey=BZTZWILYFGXIMZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 462005   

TargetMu-type opioid receptor(Human)
Nektar Therapeutics

US Patent
LigandPNGBDBM462005(Preparation of (5α)-5-{2-[2-(2-methoxyethoxy)...)
Affinity DataIC50: 55nMAssay Description:Affinities of various compounds were measured in vitro using competitive radioligand binding assays. Serial dilutions of test compounds were incubate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2021
Entry Details
Go to US Patent