BDBM462018 Preparation of 17-(oxetan-3-ylmethyl)morphinan-3-ol ::US10766864, Example 88

SMILES Oc1ccc2C[C@@H]3[C@@H]4CCCC[C@]4(CCN3CC3COC3)c2c1

InChI Key InChIKey=RTGBFYXGEAQCNA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 462018   

TargetMu-type opioid receptor(Human)
Nektar Therapeutics

US Patent
LigandPNGBDBM462018(Preparation of 17-(oxetan-3-ylmethyl)morphinan-3-o...)
Affinity DataIC50: 55nMAssay Description:Affinities of various compounds were measured in vitro using competitive radioligand binding assays. Serial dilutions of test compounds were incubate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2021
Entry Details
Go to US Patent