BDBM462022 1-(2-methoxyethyl)-3-((4aR,5R,11bR)-14-methyl-2,3,4,4a,5,6-hexahydro-1H-5,11b-(epiminoethano)phenanthro[3,2-d]thiazol-9-yl)guanidine ::US10766864, Example 92

SMILES COCCNC(=N)Nc1nc2cc3c(C[C@@H]4[C@@H]5CCCC[C@]35CCN4C)cc2s1

InChI Key InChIKey=VRANSLSVODJKTA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 462022   

TargetMu-type opioid receptor(Human)
Nektar Therapeutics

US Patent
LigandPNGBDBM462022(1-(2-methoxyethyl)-3-((4aR,5R,11bR)-14-methyl-2,3,...)
Affinity DataIC50: 550nMAssay Description:Affinities of various compounds were measured in vitro using competitive radioligand binding assays. Serial dilutions of test compounds were incubate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2021
Entry Details
US Patent