BDBM462023 Preparation of 17-(2-methoxyethyl)-N-(pyridin-4-yl)morphinan-3-amine ::US10766864, Example 93

SMILES COCCN1CC[C@]23CCCC[C@H]2[C@H]1Cc1ccc(Nc2ccncc2)cc31

InChI Key InChIKey=RVLZSXXTLPHBIC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 462023   

TargetMu-type opioid receptor(Human)
Nektar Therapeutics

US Patent
LigandPNGBDBM462023(Preparation of 17-(2-methoxyethyl)-N-(pyridin-4-yl...)
Affinity DataIC50: 55nMAssay Description:Affinities of various compounds were measured in vitro using competitive radioligand binding assays. Serial dilutions of test compounds were incubate...More data for this Ligand-Target Pair
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Date in BDB:
4/26/2021
Entry Details
Go to US Patent