BDBM462028 Preparation of 17-[2-(2-methoxyethoxy)ethyl]-N-(pyridin-4-yl)morphinan-3-amine ::US10766864, Example 98

SMILES COCCOCCN1CC[C@]23CCCC[C@H]2[C@H]1Cc1ccc(Nc2ccncc2)cc31

InChI Key InChIKey=IVUYTIOTZPFQNJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 462028   

TargetMu-type opioid receptor(Human)
Nektar Therapeutics

US Patent
LigandPNGBDBM462028(Preparation of 17-[2-(2-methoxyethoxy)ethyl]-N-(py...)
Affinity DataIC50: 550nMAssay Description:Affinities of various compounds were measured in vitro using competitive radioligand binding assays. Serial dilutions of test compounds were incubate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2021
Entry Details
US Patent