BDBM462035 Preparation of N-((4bR,8aR,9R)-11-(2-(2-methoxyethoxy)ethyl)-6,7,8,8a,9,10-hexahydro-5H-9,4b-(epiminoethano)phenanthren-3-yl)thiazol-2-amine ::US10766864, Example 105

SMILES COCCOCCN1CC[C@]23CCCC[C@H]2[C@H]1Cc1ccc(Nc2nccs2)cc31

InChI Key InChIKey=QLECEANEMQBWRJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 462035   

TargetMu-type opioid receptor(Human)
Nektar Therapeutics

US Patent
LigandPNGBDBM462035(Preparation of N-((4bR,8aR,9R)-11-(2-(2-methoxyeth...)
Affinity DataIC50: 550nMAssay Description:Affinities of various compounds were measured in vitro using competitive radioligand binding assays. Serial dilutions of test compounds were incubate...More data for this Ligand-Target Pair
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Date in BDB:
4/26/2021
Entry Details
US Patent