BDBM462036 Preparation of (4bR,8aR,9R)-3-(furan-3-yl)-11-(2-(2-methoxyethoxy)ethyl)-6,7,8,8a,9,10-hexahydro-5H-9,4b-(epiminoethano)phenanthrene ::US10766864, Example 106

SMILES COCCOCCN1CC[C@]23CCCC[C@H]2[C@H]1Cc1ccc(cc31)-c1ccoc1

InChI Key InChIKey=SILMVTUHMWZGJA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 462036   

TargetMu-type opioid receptor(Human)
Nektar Therapeutics

US Patent
LigandPNGBDBM462036(Preparation of (4bR,8aR,9R)-3-(furan-3-yl)-11-(2-(...)
Affinity DataIC50: 550nMAssay Description:Affinities of various compounds were measured in vitro using competitive radioligand binding assays. Serial dilutions of test compounds were incubate...More data for this Ligand-Target Pair
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Date in BDB:
4/26/2021
Entry Details
US Patent