BDBM462054 N-((3-(difluoromethyl)-1-(4- (trifluoromethyl)phenyl)-1H- pyrazol-4-yl)methyl)-2-(4- fluorophenylsulfonyl) cyclobutanecarboxamide (Enantiomer 2)::US10766878, Example 18

SMILES FC(F)c1nn(cc1CNC(=O)C1CCC1S(=O)(=O)c1ccc(F)cc1)-c1ccc(cc1)C(F)(F)F

InChI Key InChIKey=AXVJKWISWYSMEO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 462054   

LigandPNGBDBM462054(N-((3-(difluoromethyl)-1-(4- (trifluoromethyl)phen...)
Affinity DataIC50: 96nMAssay Description:IC50 values (effective concentration) of compounds on the human and rat TRPA1 channels were determined using a FLIPR Tetra instrument. CHO cells expr...More data for this Ligand-Target Pair
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Date in BDB:
4/26/2021
Entry Details
US Patent