BDBM464590 CIS-1-(Cyclobutyl-methyl)-8-methylamino-3-(2-methylsulfonyl-ethyl)-8-phenyl- 1,3-diazaspiro[4.5]decan-2-one::US10793556, Example SC_4010

SMILES CN[C@]1(CC[C@]2(CN(CCS(C)(=O)=O)C(=O)N2CC2CCC2)CC1)c1ccccc1

InChI Key InChIKey=FGXKRDBJUXNYKT-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 464590   

TargetNociceptin receptor(Human)
Gruenenthal

US Patent
LigandPNGBDBM464590(US10793556, Example SC_4010 | CIS-1-(Cyclobutyl-me...)
Affinity DataKi:  9.5nMAssay Description:The hNOP receptor binding assay was performed as homogeneous SPA-assay (scintillation proximity assay) using the assay buffer 50 mM TRIS-HCl. 10 mM M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2021
Entry Details
US Patent

TargetMu-type opioid receptor(Human)
Gruenenthal

US Patent
LigandPNGBDBM464590(US10793556, Example SC_4010 | CIS-1-(Cyclobutyl-me...)
Affinity DataKi:  87nMAssay Description:The hMOP receptor binding assay was performed as homogeneous SPA-assay (scintillation proximity assay) using the assay buffer 50 mM TRIS-HCl (pH 7.4)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2021
Entry Details
US Patent