BDBM4647 Anilinoquinazoline deriv. 30::N-(4-chloro-2-fluorophenyl)-6-methoxy-7-[2-(1H-1,2,3-triazol-1-yl)ethoxy]quinazolin-4-amine

SMILES COc1cc2c(Nc3ccc(Cl)cc3F)ncnc2cc1OCCn1ccnn1

InChI Key InChIKey=ZDUNROKMXDSWQP-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 4647   

LigandPNGBDBM4647(N-(4-chloro-2-fluorophenyl)-6-methoxy-7-[2-(1H-1,2...)
Affinity DataIC50: 10nMT: 2°CAssay Description:An ELISA assay was used to determine the ability of inhibitor to inhibit VEGF-R RTK activity. The compounds were incubated with enzyme 20 min at room...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2005
Entry Details Article
PubMed
LigandPNGBDBM4647(N-(4-chloro-2-fluorophenyl)-6-methoxy-7-[2-(1H-1,2...)
Affinity DataIC50: 300nMT: 2°CAssay Description:An ELISA assay was used to determine the ability of inhibitor to inhibit VEGF-R RTK activity. The compounds were incubated with enzyme 20 min at room...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2005
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
Astrazeneca

LigandPNGBDBM4647(N-(4-chloro-2-fluorophenyl)-6-methoxy-7-[2-(1H-1,2...)
Affinity DataIC50: 1.80E+3nMT: 2°CAssay Description:An ELISA assay was used to determine the ability of inhibitor to inhibit VEGF-R RTK activity. The compounds were incubated with enzyme 20 min at room...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2005
Entry Details Article
PubMed