BDBM465037 US10793563, Compound I-370

SMILES FC(F)(F)c1ccc2ncc(-c3nccc(n3)N3CCN(CC4C5COCC45)C(C3)c3cn[nH]c3)n2c1

InChI Key InChIKey=RHBOCGNXXYHHII-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 465037   

TargeteIF-2-alpha kinase GCN2(Human)
Merck Patent

US Patent
LigandPNGBDBM465037(US10793563, Compound I-370)
Affinity DataIC50: 10nMAssay Description:An assay buffer containing GCN2 kinase and (RS)7 was prepared. 4.7 μL of this stock solution was placed per well of a black, low volume, 384-wel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2021
Entry Details
US Patent