BDBM4652 Anilinoquinazoline deriv. 35::N-(4-bromo-2,6-difluorophenyl)-6-methoxy-7-[2-(1H-1,2,3-triazol-1-yl)ethoxy]quinazolin-4-amine

SMILES COc1cc2c(Nc3c(F)cc(Br)cc3F)ncnc2cc1OCCn1ccnn1

InChI Key InChIKey=SAZIXFAROZCPDO-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 4652   

LigandPNGBDBM4652(N-(4-bromo-2,6-difluorophenyl)-6-methoxy-7-[2-(1H-...)
Affinity DataIC50: 40nMT: 2°CAssay Description:An ELISA assay was used to determine the ability of inhibitor to inhibit VEGF-R RTK activity. The compounds were incubated with enzyme 20 min at room...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2005
Entry Details Article
PubMed
LigandPNGBDBM4652(N-(4-bromo-2,6-difluorophenyl)-6-methoxy-7-[2-(1H-...)
Affinity DataIC50: 800nMT: 2°CAssay Description:An ELISA assay was used to determine the ability of inhibitor to inhibit VEGF-R RTK activity. The compounds were incubated with enzyme 20 min at room...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2005
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
Astrazeneca

LigandPNGBDBM4652(N-(4-bromo-2,6-difluorophenyl)-6-methoxy-7-[2-(1H-...)
Affinity DataIC50: 6.10E+3nMT: 2°CAssay Description:An ELISA assay was used to determine the ability of inhibitor to inhibit VEGF-R RTK activity. The compounds were incubated with enzyme 20 min at room...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2005
Entry Details Article
PubMed