BDBM466120 US10793580, Example 220::[3-(1-ethyl-8-oxo-spiro[6,7- dihydro-4H-pyrazolo[3,4- c]azepine-5,4'-tetra- hydropyran]-3-yl)-2,2- dimethyl-propyl] 4-(di- methylcarbamoyl)benzoate

SMILES CCn1nc(CC(C)(C)COC(=O)c2ccc(cc2)C(=O)N(C)C)c2CC3(CCOCC3)CNC(=O)c12

InChI Key InChIKey=QVUDZAYCZNVQJT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 466120   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Leo Pharma

US Patent
LigandPNGBDBM466120([3-(1-ethyl-8-oxo-spiro[6,7- dihydro-4H-pyrazolo[3...)
Affinity DataIC50: 100nMAssay Description:The human PDE4D catalytic domain (UniProt no. Q08499 [S380-L740]) was incubated with a mixture of non-labelled cAMP (cyclic adenosine monophosphate) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2021
Entry Details
US Patent