BDBM466255 US10793582, Example 75

SMILES CCOc1nc(nc2nc(sc12)N1CCC[C@@H]1C(=O)NCc1ccccc1)C1CCOCC1

InChI Key InChIKey=ZUMCFMQMRURVIK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 466255   

TargetKynurenine/alpha-aminoadipate aminotransferase, mitochondrial(Human)
Mitsubishi Tanabe Pharma

US Patent
LigandPNGBDBM466255(US10793582, Example 75)
Affinity DataIC50: 95nMAssay Description:To a reaction mixture (45 μL) containing 3.0 μmol/L kynurenine, 10 μmol/L pyridoxal phosphate, 2.0 ng/μL human recombinant KAT-II...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2021
Entry Details
Go to US Patent