BDBM466613 6-{-[5-(4-Fluorophenoxy)-4-methoxypyridine-2-carbonyl]piperidin-4-yl}-5-methylpyridazin-3-amine trifluoroacetic acid::US10800757, Compound 29::US10889568, Compound 29

SMILES COc1cc(ncc1Oc1ccc(F)cc1)C(=O)N1CCC(CC1)c1nnc(N)cc1C

InChI Key InChIKey=FYEHZCHYPSYCHO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 466613   

TargetShort transient receptor potential channel 6(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM466613(US10889568, Compound 29 | 6-{-[5-(4-Fluorophenoxy)...)
Affinity DataIC50: 110nMAssay Description:This screening assay measures TRPC6 (transient receptor potential cation channel, subfamily C, member 6) ion channel activation via addition either o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent

TargetShort transient receptor potential channel 6(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM466613(US10889568, Compound 29 | 6-{-[5-(4-Fluorophenoxy)...)
Affinity DataIC50: 110nMAssay Description:The commercially available HEK293/TREx line (Invitrogen) was stably transfected with a TRPC6 construct and screened by conventional calcium imaging t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2021
Entry Details
US Patent