BDBM467324 US10800786, Example 1.07

SMILES CC(C)(C)C(=O)Nc1cc(cnc1COC(=O)N1CCC2=C(CCN(C2)C(=O)c2ccc3[nH]nnc3c2)C1)C(F)(F)F

InChI Key InChIKey=JIWLLTXUMQGPRU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 467324   

TargetAutotaxin(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM467324(US10800786, Example 1.07)
Affinity DataIC50: 17nMAssay Description:ATX inhibition was measured by a fluorescence quenching assay using a specifically labeled substrate analogue (MR121 substrate). To obtain this MR121...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent