BDBM467333 US10800786, Example 2.05

SMILES CC(C)(C)C(=O)Nc1cc(Cl)c(Cl)nc1COC(=O)N1CC2=C(C1)CN(C2)C(=O)N1CCc2c(O)noc2C1

InChI Key InChIKey=CFGDJUZJZKKKOC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 467333   

TargetAutotaxin(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM467333(US10800786, Example 2.05)
Affinity DataIC50: 7nMAssay Description:ATX inhibition was measured by a fluorescence quenching assay using a specifically labeled substrate analogue (MR121 substrate). To obtain this MR121...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent