BDBM468409 (R) N-(2-chloro-3′-(5-((3-hydroxypyrrolidin-1-yl)methyl)-1-methyl-2-oxo-1,2-dihydropyridine-3-carboxamido)-2′-methylbiphenyl-3-yl)-1,5-dimethyl-4,5,6,7-tetrahydro-1H-imidazo[4,5-c]pyridine-2-carboxamide::US10806785, Example 48

SMILES CN1CCc2c(C1)nc(C(=O)Nc1cccc(c1Cl)-c1cccc(NC(=O)c3cc(CN4CC[C@@H](O)C4)cn(C)c3=O)c1C)n2C

InChI Key InChIKey=DBKRYKSFMAQJMM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 468409   

LigandPNGBDBM468409(US10806785, Example 48 | (R) N-(2-chloro-3′-...)
Affinity DataIC50: 0.100nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
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Date in BDB:
6/11/2021
Entry Details
US Patent