BDBM468445 US10806785, Example 87::trans-4-(2-(2-((2,2'-dichloro- 3'-(5-(cyclopropylmethyl)-1- methyl-4,5,6,7-tetrahydro-1H- imidazo[4,5-c]pyridine-2- carboxamido)-[1,1'-biphenyl]- 3-yl)carbamoyl)-1-methyl- 1,4,6,7-tetrahydro-5H- imidazo[4,5-c]pyridin-5- yl)ethyl)cyclohexane-1- carboxylic acid

SMILES Cn1c2CCN(CC[C@H]3CC[C@@H](CC3)C(O)=O)Cc2nc1C(=O)Nc1cccc(c1Cl)-c1cccc(NC(=O)c2nc3CN(CC4CC4)CCc3n2C)c1Cl

InChI Key InChIKey=HBVPDOPMPMESME-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 468445   

LigandPNGBDBM468445(US10806785, Example 87 | trans-4-(2-(2-((2,2'-dich...)
Affinity DataIC50: 0.100nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent