BDBM468466 4-(2-((2'-chloro- 2-methyl-3'-(1- methyl-5-(tetrahydro- 2H-pyran- 4-yl)-4,5,6,7- tetrahydro-1H- imidazo[4,5-c] pyridine-2- carboxamido)- [1,1'-biphenyl]- 3-yl)carbamoyl)- 1-methyl- 1,4,6,7- tetrahydro-5H- imidazo[4,5-c] pyridin-5-yl)-1- methylcyclohexane-1- carboxylic acid::US10806785, Example 108

SMILES Cc1c(NC(=O)c2nc3CN(CCc3n2C)C2CCC(C)(CC2)C(O)=O)cccc1-c1cccc(NC(=O)c2nc3CN(CCc3n2C)C2CCOCC2)c1Cl

InChI Key InChIKey=CFJNIPDVNIOKHK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 468466   

LigandPNGBDBM468466(US10806785, Example 108 | 4-(2-((2'-chloro- 2-meth...)
Affinity DataIC50: 0.100nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
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Date in BDB:
6/11/2021
Entry Details
US Patent