BDBM468551 4-((2-(2,2'- dichloro- 3'-(1- methyl-5- (tetrahydro- 2H- pyran-4-yl)- 4,5,6,7- tetrahydro- 1H-imidazo [4,5-c] pyridine-2- carboxamido) biphenyl-3- ylcarba- moyl)-1- methyl-6,7- dihydro-1H- imidazo[4,5-::US10806785, Example 179::US11401279, Example 179

SMILES Cn1c2CCN(CC34CCC(CC3)(C4)C(O)=O)Cc2nc1C(=O)Nc1cccc(c1Cl)-c1cccc(NC(=O)c2nc3CN(CCc3n2C)C2CCOCC2)c1Cl

InChI Key InChIKey=KSOUYEWJMARSHA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 468551   

LigandPNGBDBM468551(4-((2-(2,2'- dichloro- 3'-(1- methyl-5- (tetrahydr...)
Affinity DataIC50: 0.550nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
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LigandPNGBDBM468551(4-((2-(2,2'- dichloro- 3'-(1- methyl-5- (tetrahydr...)
Affinity DataIC50: 18nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2022
Entry Details
Go to US Patent