BDBM468552 4-((2-(2,2′-dichloro-3′-(5-(2-hydroxyethyl)-1-methyl-4,5,6,7-tetrahydro-1H-imidazo[4,5-c]pyridine-2-carboxamido)biphenyl-3-ylcarbamoyl)-1-methyl-6,7-dihydro-1H-imidazo[4,5-c]pyridin-5(4H)-yl)methyl)bicyclo[2.2.1]heptane-1-carboxylic acid::CN110267953A, Example 180::US10806785, Example 180::US11401279, Example 180

SMILES Cn1c2CCN(CCO)Cc2nc1C(=O)Nc1cccc(c1Cl)-c1cccc(NC(=O)c2nc3CN(CC45CCC(CC4)(C5)C(O)=O)CCc3n2C)c1Cl

InChI Key InChIKey=WBZNEDUMIHJBGD-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 468552   

LigandPNGBDBM468552(4-((2-(2,2′-dichloro-3′-(5-(2-hydroxye...)
Affinity DataIC50: 0.100nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
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LigandPNGBDBM468552(4-((2-(2,2′-dichloro-3′-(5-(2-hydroxye...)
Affinity DataIC50: 1.5nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2022
Entry Details
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TargetProgrammed cell death 1 ligand/protein 1(Human)
Shenzhen Chipscreen Biosciences

US Patent
LigandPNGBDBM468552(4-((2-(2,2′-dichloro-3′-(5-(2-hydroxye...)
Affinity DataIC50: 4.62nMAssay Description:The experiment process was carried out according to the flow required in the operating manual of the test reagent.The process was as follows:(1) Expe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/12/2024
Entry Details
Go to US Patent