BDBM470262 US10815206, Compound I-39

SMILES CN1c2cc(CN3CCN4N=C(NC4C3)C(F)(F)F)ccc2OC[C@H](NC(=O)c2ncn(Cc3ccccc3)n2)C1=O

InChI Key InChIKey=XKTBINIMZUAUGC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 470262   

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Rigel Pharmaceuticals

US Patent
LigandPNGBDBM470262(US10815206, Compound I-39)
Affinity DataIC50: 36.4nMAssay Description:A 500 ml stock volume of 5× Reaction Kinase Buffer was made by mixing 1000 μl of 1M MgCl2, 500 μl of 1M Tris-HCL pH7.4, 0.5 mg/ml (25 mg) o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2021
Entry Details
US Patent