BDBM470269 US10815206, Compound I-50

SMILES CN5C(=O)[C@@H](NC(=O)c2n[nH]c(Cc1ccccc1)n2)COc4ccc(C#CC3(O)CCC3)cc45

InChI Key InChIKey=JOPXYPLAXUBVQB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 470269   

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Rigel Pharmaceuticals

US Patent
LigandPNGBDBM470269(US10815206, Compound I-50)
Affinity DataIC50: 23.4nMAssay Description:A 500 ml stock volume of 5× Reaction Kinase Buffer was made by mixing 1000 μl of 1M MgCl2, 500 μl of 1M Tris-HCL pH7.4, 0.5 mg/ml (25 mg) o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/13/2021
Entry Details
US Patent