BDBM471699 US10822342, Compound 7

SMILES CCn1cc2nc(N)nc(-c3cn(C4CN(CC5CC5)C4)c4cc(F)c(cc34)C#CC(C)(C)O)c2n1

InChI Key InChIKey=YEHDXTBUFSOBME-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 471699   

TargetMitogen-activated protein kinase kinase kinase 14(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM471699(US10822342, Compound 7)
Affinity DataIC50: 60nMAssay Description:NIK/MAP3K14 auto-phosphorylation activity was measured using the AlphaScreen (αscreen) format (Perkin Elmer). All compounds tested were dissolve...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2021
Entry Details
US Patent