BDBM471820 1-cyclopropyl-N-((R)-1-(5- (ethylsulfonyl)pyridin-2-yl)-2-hydroxyethyl)- 2-(((1r,4R)-4- (trifluoromethyl)cyclohexyl)methyl)-1H- benzo[d]imidazole-5-carboxamide::US10829448, Compound BE-28

SMILES CCS(=O)(=O)c1ccc(nc1)[C@H](CO)NC(=O)c1ccc2n(C3CC3)c(CC3CCC(CC3)C(F)(F)F)nc2c1

InChI Key InChIKey=WGVDGZZVENHSQZ-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 471820   

TargetNuclear receptor ROR-gamma(Human)
Vitae Pharmaceuticals

US Patent
LigandPNGBDBM471820(1-cyclopropyl-N-((R)-1-(5- (ethylsulfonyl)pyridin-...)
Affinity DataKi: <100nMAssay Description:Compounds described herein were tested for ability to bind to RORγ in a cell-free competition assay with commercially available radio-ligand (RL...More data for this Ligand-Target Pair
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Date in BDB:
6/28/2021
Entry Details
US Patent