BDBM471825 1-cyclopropyl-N-((R)-2-hydroxy-1-(4- (methylsulfonyl)phenyl)ethyl)-2-(((1r,4R)-4- (trifluoromethyl)cyclohexyl)methyl)-1H- benzo[d]imidazole-5-carboxamide::US10829448, Compound BE-32

SMILES CS(=O)(=O)c1ccc(cc1)[C@H](CO)NC(=O)c1ccc2n(C3CC3)c(CC3CCC(CC3)C(F)(F)F)nc2c1

InChI Key InChIKey=HKHIWEKSQKWELQ-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 471825   

TargetNuclear receptor ROR-gamma(Human)
Vitae Pharmaceuticals

US Patent
LigandPNGBDBM471825(1-cyclopropyl-N-((R)-2-hydroxy-1-(4- (methylsulfon...)
Affinity DataKi: <100nMAssay Description:Compounds described herein were tested for ability to bind to RORγ in a cell-free competition assay with commercially available radio-ligand (RL...More data for this Ligand-Target Pair
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Date in BDB:
6/28/2021
Entry Details
US Patent