BDBM472254 US10829481, Compound I-76::methyl 2-(1-((2,2-difluorobenzo[d][1,3]dioxol-4-yl)methyl)-2-

SMILES COC(=O)C(NC(=O)c1ccc2n(Cc3cccc4OC(F)(F)Oc34)c(nc2c1)C(F)(F)F)C1CCN(CC1)S(C)(=O)=O

InChI Key InChIKey=DONOTCQEDJPVKP-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 472254   

TargetNuclear receptor ROR-gamma(Human)
Vitae Pharmaceuticals

US Patent
LigandPNGBDBM472254(US10829481, Compound I-76 | methyl 2-(1-((2,2-difl...)
Affinity DataKi: <100nMAssay Description:Compounds described herein were tested for ability to bind to RORγ in a cell-free competition assay with commercially available radio-ligand (RL...More data for this Ligand-Target Pair
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Date in BDB:
6/28/2021
Entry Details
US Patent