BDBM472297 2-cyclopropyl-1-(3-(difluoromethoxy)benzyl)-N-(4-::US10829481, Compound I-113

SMILES CCS(=O)(=O)c1ccc(CNC(=O)c2ccc3n(Cc4cccc(OC(F)F)c4)c(nc3c2)C2CC2)cc1

InChI Key InChIKey=QQUWAQNLGQWKIF-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 472297   

TargetNuclear receptor ROR-gamma(Human)
Vitae Pharmaceuticals

US Patent
LigandPNGBDBM472297(2-cyclopropyl-1-(3-(difluoromethoxy)benzyl)-N-(4- ...)
Affinity DataKi: <100nMAssay Description:Compounds described herein were tested for ability to bind to RORγ in a cell-free competition assay with commercially available radio-ligand (RL...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2021
Entry Details
US Patent