BDBM472308 2-cyclopropyl-1-(2,3-dimethoxybenzyl)-N-(4-(ethylsulfonyl)benzyl)-::US10829481, Compound I-119

SMILES CCS(=O)(=O)c1ccc(CNC(=O)c2ccc3n(Cc4cccc(OC)c4OC)c(nc3c2)C2CC2)cc1

InChI Key InChIKey=PGYXUXKOYRWSSJ-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 472308   

TargetNuclear receptor ROR-gamma(Human)
Vitae Pharmaceuticals

US Patent
LigandPNGBDBM472308(2-cyclopropyl-1-(2,3-dimethoxybenzyl)-N-(4-(ethyls...)
Affinity DataKi: <100nMAssay Description:Compounds described herein were tested for ability to bind to RORγ in a cell-free competition assay with commercially available radio-ligand (RL...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2021
Entry Details
US Patent