BDBM47238 US9012475, MLN8237

SMILES COc1cc(Nc2ncc3CN=C(c4c(F)cccc4OC)c4c(Cl)cccc4-c3n2)ccc1C(O)=O

InChI Key InChIKey=ORGQNRJTEJDZTI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 47238   

TargetAurora kinase A(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM47238(US9012475, MLN8237)
Affinity DataIC50: 0.600nMpH: 7.4Assay Description:The method for measuring the in-vitro inhibitory activity of a test compound against Aurora B kinase activity was substantially the same as in the ca...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2015
Entry Details
US Patent

TargetAurora kinase B(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM47238(US9012475, MLN8237)
Affinity DataIC50: 90nMpH: 7.4Assay Description:The method for measuring the in-vitro inhibitory activity of a test compound against Aurora B kinase activity was substantially the same as in the ca...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2015
Entry Details
US Patent