BDBM472564 US10829487, Example I-43

SMILES C[C@@H](Nc1nc(C)nc2cc(=O)n(cc12)[C@H]1C[C@H](O)C1)c1cccc(c1C)C(F)(F)F

InChI Key InChIKey=OPWSDOPRIRMMJL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 472564   

TargetGTPase KRas [1-169,G12D]/Son of sevenless homolog 1 [564-1049](Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM472564(US10829487, Example I-43)
Affinity DataIC50: 5nMAssay Description:Compounds are diluted to a final start concentration of 100 μM and are tested in duplicate. Assay-ready plates (ARPs) are generated using an Acc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2021
Entry Details
US Patent