BDBM472829 US10829500, Exam. 4

SMILES NC1=N[C@@](CF)(C[S@]2(=O)=NCCCCN12)c1nc(NC(=O)c2ccc(cn2)C#N)ccc1F

InChI Key InChIKey=VGEZZRMHKSHFMA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 472829   

TargetBeta-secretase 1(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM472829(US10829500, Exam. 4)
Affinity DataIC50: 96nMAssay Description:It has been found that the compounds of the present invention are associated with inhibition of BACE1 activity. More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2021
Entry Details
Go to US Patent