BDBM472901 Piperidin-4-ylmethyl 4-fluoro-4-(((2-(6-phenylpyridin- 3-yl)cyclopropyl)amino)methyl) piperidine-1-carboxylate::US10836743, Compound A115

SMILES FC1(CNC2CC2c2ccc(nc2)-c2ccccc2)CCN(CC1)C(=O)OCC1CCNCC1

InChI Key InChIKey=XFVDGDFJWNNXGS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 472901   

TargetLysine-specific histone demethylase 1A(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandPNGBDBM472901(Piperidin-4-ylmethyl 4-fluoro-4-(((2-(6-phenylpyri...)
Affinity DataIC50: 125nMAssay Description:Screening method: lysine-specific demethylase 1 (LSD1) activity screeningInstrument: microplate reader Envision (PerkinElmer, USA).MATERIALS: Human r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2021
Entry Details
US Patent