BDBM473747 US10844077, Compound I-6

SMILES Cc1cccc(C)c1NC(=O)c1cnc(Nc2ccnc(N[C@@H]3CCCN(C3)C(=O)C=C)n2)s1

InChI Key InChIKey=QDGTXHCHKQBECZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 473747   

TargetTyrosine-protein kinase BTK(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM473747(US10844077, Compound I-6)
Affinity DataIC50: 1.90nMAssay Description:The inhibitory activities of exemplary compounds described herein against select protein kinases.More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
US Patent

TargetTyrosine-protein kinase HCK(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM473747(US10844077, Compound I-6)
Affinity DataIC50: 4.24nMAssay Description:The inhibitory activities of exemplary compounds described herein against select protein kinases.More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
US Patent