BDBM473754 US10844077, Compound III-1

SMILES C=CC(=O)N1CC[C@@H](C1)Nc1nccc(Nc2nc3ccc(Oc4ccccc4)nc3s2)n1

InChI Key InChIKey=MCAASVHSHOYFNM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 473754   

TargetTyrosine-protein kinase BTK(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM473754(US10844077, Compound III-1)
Affinity DataIC50: 86.6nMAssay Description:The inhibitory activities of exemplary compounds described herein against select protein kinases.More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
US Patent

TargetTyrosine-protein kinase HCK(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM473754(US10844077, Compound III-1)
Affinity DataIC50: 1.82E+3nMAssay Description:The inhibitory activities of exemplary compounds described herein against select protein kinases.More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
US Patent