BDBM474449 US10858373, Example 47

SMILES CN(C1COC2(C1)CCN(CC2)C(=O)ON1C(=O)CCC1=O)S(=O)(=O)Cc1ccccc1

InChI Key InChIKey=GTTDKAZTTJGHIJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 474449   

TargetMonoglyceride lipase(Human)
Pfizer

US Patent
LigandPNGBDBM474449(US10858373, Example 47)
Affinity DataIC50: 23nMAssay Description:T = 30 minutes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Pfizer

US Patent
LigandPNGBDBM474449(US10858373, Example 47)
Affinity DataIC50: 192nMAssay Description:Assessment of MAGL inhibition utilizes human recombinant Monoacylglycerol Lipase and the fluorogenic substrate 7-hydroxycoumarinyl arachidonate (7-HC...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
US Patent