BDBM474488 N-acetylaminoethyl-4-(2-bromo-3-phenylbenzyloxy)-5-chloro-2-allyloxy benzylamine::US10882833, Example 3

SMILES CC(=O)NCCNCc1cc(Cl)c(OCc2cccc(c2Br)-c2ccccc2)cc1OCC=C

InChI Key InChIKey=DQAIJLLKACMEGZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 474488   

TargetProgrammed cell death 1 ligand/protein 1(Human)
Institute of Materia Medica, Chinese Academy of Medical Sciences

US Patent
LigandPNGBDBM474488(N-acetylaminoethyl-4-(2-bromo-3-phenylbenzyloxy)-5...)
Affinity DataIC50: 126nMAssay Description:1. In vitro activity evaluation: Cisbio PD-1/PD-L1 binding assay kit was applied for the detection method of in vitro enzymology level.Screening Prin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2021
Entry Details
US Patent