BDBM474499 (S) N-(4-(2-bromo-3-phenylbenzyloxy)-5-chloro-2-(cyclopropylmethoxy)benzyl)serine::US10882833, Example 14

SMILES OC[C@H](NCc1cc(Cl)c(OCc2cccc(c2Br)-c2ccccc2)cc1OCC1CC1)C(O)=O

InChI Key InChIKey=WRHJZHIIOSVAPO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 474499   

TargetProgrammed cell death 1 ligand/protein 1(Human)
Institute of Materia Medica, Chinese Academy of Medical Sciences

US Patent
LigandPNGBDBM474499((S) N-(4-(2-bromo-3-phenylbenzyloxy)-5-chloro-2-(c...)
Affinity DataIC50: 41.7nMAssay Description:1. In vitro activity evaluation: Cisbio PD-1/PD-L1 binding assay kit was applied for the detection method of in vitro enzymology level.Screening Prin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2021
Entry Details
US Patent