BDBM474717 US10849883, Compound 141c::US11559515, Compound 141c

SMILES CC(C)(C)OC(=O)Cn1cc(C(N)=O)c2cc(Nc3cncnc3)ccc12

InChI Key InChIKey=AJHKNJVGRWMVTA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 474717   

TargetComplement factor D(Human)
Biocryst Pharmaceuticals

US Patent
LigandPNGBDBM474717(US10849883, Compound 141c | US11559515, Compound 1...)
Affinity DataIC50: 1.00E+3nMAssay Description:An established esterolytic assay for the measurement of Factor D activity and inhibition of Factor D activity was used (Kam, C. M.; McRae, B. J.; Har...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/12/2021
Entry Details
US Patent

TargetComplement factor D(Human)
Biocryst Pharmaceuticals

US Patent
LigandPNGBDBM474717(US10849883, Compound 141c | US11559515, Compound 1...)
Affinity DataIC50: 1.00E+4nMAssay Description:An established esterolytic assay for the measurement of Factor D activity and inhibition of Factor D activity was used (Kam, C. M.; McRae, B. J.; Har...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent