BDBM475199 US10851082, NUCC-0125593

SMILES N(c1ccc(cc1)-n1cccn1)c1nccc(n1)-n1cnc2ccccc12

InChI Key InChIKey=HWKLPUXMYLCSIE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 475199   

TargetMAP kinase-interacting serine/threonine-protein kinase 1(Human)
Northwestern University

US Patent
LigandPNGBDBM475199(US10851082, NUCC-0125593)
Affinity DataIC50: 650nMAssay Description:The synthesized compounds then were tested for inhibition of the kinase activity (IC50) of Mnk1 and/or Mnk2 using the ADP monitoring assay for kinase...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/12/2021
Entry Details
Go to US Patent

TargetMAP kinase-interacting serine/threonine-protein kinase 2(Human)
Northwestern University

US Patent
LigandPNGBDBM475199(US10851082, NUCC-0125593)
Affinity DataIC50: 39nMAssay Description:The synthesized compounds then were tested for inhibition of the kinase activity (IC50) of Mnk1 and/or Mnk2 using the ADP monitoring assay for kinase...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/12/2021
Entry Details
Go to US Patent