BDBM475214 US10851082, NUCC-0176145::US10851082, NUCC-0176166

SMILES OC1CCC(CC1)Nc1nccc(n1)-n1cnc2ccccc12

InChI Key InChIKey=SSHPOTBZTFBVDB-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 475214   

TargetMAP kinase-interacting serine/threonine-protein kinase 2(Human)
Northwestern University

US Patent
LigandPNGBDBM475214(US10851082, NUCC-0176145 | US10851082, NUCC-017616...)
Affinity DataIC50: 52nMAssay Description:The synthesized compounds then were tested for inhibition of the kinase activity (IC50) of Mnk1 and/or Mnk2 using the ADP monitoring assay for kinase...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/12/2021
Entry Details
US Patent

TargetMAP kinase-interacting serine/threonine-protein kinase 2(Human)
Northwestern University

US Patent
LigandPNGBDBM475214(US10851082, NUCC-0176145 | US10851082, NUCC-017616...)
Affinity DataIC50: 63nMAssay Description:The synthesized compounds then were tested for inhibition of the kinase activity (IC50) of Mnk1 and/or Mnk2 using the ADP monitoring assay for kinase...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/12/2021
Entry Details
US Patent

TargetMAP kinase-interacting serine/threonine-protein kinase 1(Human)
Northwestern University

US Patent
LigandPNGBDBM475214(US10851082, NUCC-0176145 | US10851082, NUCC-017616...)
Affinity DataIC50: 390nMAssay Description:The synthesized compounds then were tested for inhibition of the kinase activity (IC50) of Mnk1 and/or Mnk2 using the ADP monitoring assay for kinase...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/12/2021
Entry Details
US Patent

TargetMAP kinase-interacting serine/threonine-protein kinase 1(Human)
Northwestern University

US Patent
LigandPNGBDBM475214(US10851082, NUCC-0176145 | US10851082, NUCC-017616...)
Affinity DataIC50: 400nMAssay Description:The synthesized compounds then were tested for inhibition of the kinase activity (IC50) of Mnk1 and/or Mnk2 using the ADP monitoring assay for kinase...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/12/2021
Entry Details
US Patent