BDBM475232 US10851082, NUCC-0176281

SMILES Fc1cnc(NCCc2ccncc2)nc1-n1cnc2ccccc12

InChI Key InChIKey=ZDSCMCRGHRMVAM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 475232   

TargetMAP kinase-interacting serine/threonine-protein kinase 1(Human)
Northwestern University

US Patent
LigandPNGBDBM475232(US10851082, NUCC-0176281)
Affinity DataIC50: 330nMAssay Description:The synthesized compounds then were tested for inhibition of the kinase activity (IC50) of Mnk1 and/or Mnk2 using the ADP monitoring assay for kinase...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/12/2021
Entry Details
Go to US Patent

TargetMAP kinase-interacting serine/threonine-protein kinase 2(Human)
Northwestern University

US Patent
LigandPNGBDBM475232(US10851082, NUCC-0176281)
Affinity DataIC50: 49nMAssay Description:The synthesized compounds then were tested for inhibition of the kinase activity (IC50) of Mnk1 and/or Mnk2 using the ADP monitoring assay for kinase...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/12/2021
Entry Details
Go to US Patent